EdenteV2, Main, Exploration, bibRecord, 002517

Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India

Identifieur interne : 002517 ( Main/Exploration ); précédent : 002516; suivant : 002518

Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India

Auteurs : Prathibha K. M ; Priscilla Johnson ; Mathangi Ganesh ; Arcot S. Subhashini

Source :

Journal of Clinical and Diagnostic Research : JCDR [ 2249-782X ] ; 2013.

RBID : PMC:3782905

Abstract

Background: A lack of consensus on the possible association between diabetes and salivary dysfunction motivated us to conduct this investigation on the salivary parameters in diabetic and non diabetic subjects. This could also make the use of saliva as an alternative to that of blood in the diagnosis/monitoring of diabetes mellitus.

Objectives: To compare the salivary flow rates and the salivary physical and biochemical parameters of diabetic (D) and non diabetic (ND) subjects.

Material and Methods: The participants in this study included 30 non diabetic subjects and 30 diabetic volunteers who had Type 2 Diabetes mellitus for a minimum of 2 years. Unstimulated whole saliva was collected in the fasting state. Salivary pH, flow rate and organic and inorganic constituents were evaluated. Data which was collected was statistically analysed and interpreted.

Results: Salivary pH (ND=7.09±0.29, D=6.69±0.35), flow rate (ND=0.67±0.07, D=0.46±0.02) and salivary amylase (ND=92.51±13.74, D=19.20±1.8) were significantly lower in diabetics. They had significantly higher levels of salivary glucose (ND=4.33 ± 0.29, D=17.31±2.05), total proteins (ND=424.46±237.34, D=877.29±603.84), sodium (ND=4.31±0.65, D=14.42±1.83) and potassium (ND=20.84±0.71, D=25.95±1.56) and lower levels of calcium (ND=6.39±0.5, D=4.22±0.12) in comparison to those in the non-diabetic group.

Conclusion: Significant variations were observed in salivary physical and biochemical parameters between diabetics and non diabetics. Evaluation of salivary parameters can be a cost effective and a non invasive alternative for screening, diagnosis and monitoring of diabetes, to blood.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782905

DOI: 10.7860/JCDR/2013/5749.3232
PubMed: 24086848
PubMed Central: 3782905

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India</title>
<author><name sortKey="K M, Prathibha" sort="K M, Prathibha" uniqKey="K M P" first="Prathibha" last="K. M">Prathibha K. M</name>
<affiliation><nlm:aff id="aff1"> Assistant Professor, Department of Physiology,<institution>Saveetha Medical College and Hospital</institution>
,<addr-line>Chennai, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Johnson, Priscilla" sort="Johnson, Priscilla" uniqKey="Johnson P" first="Priscilla" last="Johnson">Priscilla Johnson</name>
<affiliation><nlm:aff id="aff2"> Professor, Department of Physiology,<institution>Sri Ramachandra University</institution>
,<addr-line>Chennai, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ganesh, Mathangi" sort="Ganesh, Mathangi" uniqKey="Ganesh M" first="Mathangi" last="Ganesh">Mathangi Ganesh</name>
<affiliation><nlm:aff id="aff3"> Professor, Department Of Physiology,<institution>Chettinad Hospital and Research Institute</institution>
,<addr-line>Chennai India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Subhashini, Arcot S" sort="Subhashini, Arcot S" uniqKey="Subhashini A" first="Arcot S." last="Subhashini">Arcot S. Subhashini</name>
<affiliation><nlm:aff id="aff4"> Professor, Department of Physiology,<institution>Sri Ramachandra University</institution>
,<addr-line>Chennai, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24086848</idno>
<idno type="pmc">3782905</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782905</idno>
<idno type="RBID">PMC:3782905</idno>
<idno type="doi">10.7860/JCDR/2013/5749.3232</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">002357</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002357</idno>
<idno type="wicri:Area/Pmc/Curation">002357</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002357</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001A33</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001A33</idno>
<idno type="wicri:Area/Ncbi/Merge">004A28</idno>
<idno type="wicri:Area/Ncbi/Curation">004A28</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004A28</idno>
<idno type="wicri:doubleKey">2249-782X:2013:K M P:evaluation:of:salivary</idno>
<idno type="wicri:Area/Main/Merge">002528</idno>
<idno type="wicri:Area/Main/Curation">002517</idno>
<idno type="wicri:Area/Main/Exploration">002517</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India</title>
<author><name sortKey="K M, Prathibha" sort="K M, Prathibha" uniqKey="K M P" first="Prathibha" last="K. M">Prathibha K. M</name>
<affiliation><nlm:aff id="aff1"> Assistant Professor, Department of Physiology,<institution>Saveetha Medical College and Hospital</institution>
,<addr-line>Chennai, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Johnson, Priscilla" sort="Johnson, Priscilla" uniqKey="Johnson P" first="Priscilla" last="Johnson">Priscilla Johnson</name>
<affiliation><nlm:aff id="aff2"> Professor, Department of Physiology,<institution>Sri Ramachandra University</institution>
,<addr-line>Chennai, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ganesh, Mathangi" sort="Ganesh, Mathangi" uniqKey="Ganesh M" first="Mathangi" last="Ganesh">Mathangi Ganesh</name>
<affiliation><nlm:aff id="aff3"> Professor, Department Of Physiology,<institution>Chettinad Hospital and Research Institute</institution>
,<addr-line>Chennai India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Subhashini, Arcot S" sort="Subhashini, Arcot S" uniqKey="Subhashini A" first="Arcot S." last="Subhashini">Arcot S. Subhashini</name>
<affiliation><nlm:aff id="aff4"> Professor, Department of Physiology,<institution>Sri Ramachandra University</institution>
,<addr-line>Chennai, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><bold>Background:</bold>
 A lack of consensus on the possible association between diabetes and salivary dysfunction motivated us to conduct this investigation on the salivary parameters in diabetic and non diabetic subjects. This could also make the use of saliva as an alternative to that of blood in the diagnosis/monitoring of diabetes mellitus.</p>
<p><bold>Objectives:</bold>
 To compare the salivary flow rates and the salivary physical and biochemical parameters of diabetic (D) and non diabetic (ND) subjects.</p>
<p><bold>Material and Methods:</bold>
 The participants in this study included 30 non diabetic subjects and 30 diabetic volunteers who had Type 2 Diabetes mellitus for a minimum of 2 years. Unstimulated whole saliva was collected in the fasting state. Salivary pH, flow rate and organic and inorganic constituents were evaluated. Data which was collected was statistically analysed and interpreted.</p>
<p><bold>Results:</bold>
 Salivary pH (ND=7.09±0.29, D=6.69±0.35), flow rate (ND=0.67±0.07, D=0.46±0.02) and salivary amylase (ND=92.51±13.74, D=19.20±1.8) were significantly lower in diabetics. They had significantly higher levels of salivary glucose (ND=4.33 ± 0.29, D=17.31±2.05), total proteins (ND=424.46±237.34, D=877.29±603.84), sodium (ND=4.31±0.65, D=14.42±1.83) and potassium (ND=20.84±0.71, D=25.95±1.56) and lower levels of calcium (ND=6.39±0.5, D=4.22±0.12) in comparison to those in the non-diabetic group.</p>
<p><bold>Conclusion:</bold>
 Significant variations were observed in salivary physical and biochemical parameters between diabetics and non diabetics. Evaluation of salivary parameters can be a cost effective and a non invasive alternative for screening, diagnosis and monitoring of diabetes, to blood.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Ganesh, Mathangi" sort="Ganesh, Mathangi" uniqKey="Ganesh M" first="Mathangi" last="Ganesh">Mathangi Ganesh</name>
<name sortKey="Johnson, Priscilla" sort="Johnson, Priscilla" uniqKey="Johnson P" first="Priscilla" last="Johnson">Priscilla Johnson</name>
<name sortKey="K M, Prathibha" sort="K M, Prathibha" uniqKey="K M P" first="Prathibha" last="K. M">Prathibha K. M</name>
<name sortKey="Subhashini, Arcot S" sort="Subhashini, Arcot S" uniqKey="Subhashini A" first="Arcot S." last="Subhashini">Arcot S. Subhashini</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002517 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002517 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    EdenteV2
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:3782905
   |texte=   Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:24086848" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a EdenteV2

This area was generated with Dilib version V0.6.32.
Data generation: Thu Nov 30 15:26:48 2017. Site generation: Tue Mar 8 16:36:20 2022

Serveur d'exploration sur le patient édenté

Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India

Evaluation of Salivary Profile among Adult Type 2 Diabetes Mellitus Patients in South India

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le patient édenté
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.